CBD and THC have both been shown to provide therapeutic promise for Parkinson’s Disease during pre-clinical trials and further investigation is warranted. Additional research may shed light on the correct dosing of THC and CBD individually or combined to most effectively manage Parkinson’s Disease. There are many different stages of Parkinson’s Disease and more research is needed to determine the best therapeutic dosing of cannabis.
There are also numerous subjective reports of how regular medical cannabis use has improved patient’s symptoms. It has been shown to reduce tremors, decrease muscle spasticity and improve balance. One U.K. woman, Diane Lee, reported that taking daily cannabis oil cured her tremors and allowed her to come off of other medications which were creating horrible side effects. Ms. Lee had been taking sertraline for several years and found that she could not hold things or sleep adequately due to the medication’s effects. Ms. Lee reported that she takes 2 drops of cannabis oil in the morning, and two at night, and has found that the dose is effective at controlling her tremors. Within 10 minutes of taking the cannabis oil Ms. Lee is visibly calmer and does not shake.
The endocannabinoid system plays a key role and regulating the lifespan of a cell, which is something vitally important in the central nervous system (CNS). A study in the Journal of Neurochemistry demonstrated the neuroprotectant effects of cannabidiol (CBD) in patients with Alzheimer’s patients. Alzheimer’s and Parkinson’s are similar disease processes in that they are both neurodegenerative. Therefore, cannabis has a neuroprotectant effect and may slow down cell death in the brain.
Daily cannabis use may also reduce the number of cell deaths in the substantia nigra and prevent severe symptoms from occurring in later stages of Parkinson’s Disease.
Cannabis consumptions also demonstrate analgesic effects in the body according to the European Journal of Internal Medicine. After six months of daily cannabis consumption, 18% of patients reported that they had reduced or eliminated opioid medications. After six months, 94% of patients reported an improvement in their condition. Cannabis may very well assist patients in managing their condition without the use of addictive opioids and other habit-forming medications.
The above study also recommends starting low and going slow. Cannabis should be introduced in small doses, over a period of two weeks. When symptoms are effectively managed the correct dose has been achieved.