Research into cannabis for epilepsy is robust and growing, with several controlled studies showing medical marijuana can reduce seizures in patients of all ages. Medical marijuana has been used to treat epilepsy in Canada for many years, with increasingly strong scientific support.
The effectiveness of cannabis for epilepsy is primarily linked to how cannabinoids interact with the body’s endocannabinoid system, which plays a role in regulating neurological activity:
- Anti-seizure properties: CBD (cannabidiol) has demonstrated significant anticonvulsant properties in clinical trials
- Neuroprotective effects: Cannabinoids may help protect brain cells during seizure activity
- Reduced excitotoxicity: Cannabis compounds may help regulate excessive neuronal firing
- Anti-inflammatory action: Reducing brain inflammation that can trigger seizures
Studies show CBD is the most helpful compound to treat most neurological symptoms associated with epilepsy. However, THC can also work well for epilepsy symptoms, and a combination of CBD and THC often works best, which is commonly known as the ‘entourage effect’.
In 2018, the FDA approved Epidiolex, a CBD-based medication, for treating specific forms of epilepsy, further validating cannabis compounds as legitimate treatment options.
It’s important to note that while research is promising, cannabis treatment should be used under proper medical guidance, especially for epilepsy, where proper dosing and monitoring are essential.