Considerable evidence demonstrates that manipulation of the endocannabinoid system regulates nausea and vomiting in humans and other animals. The anti-emetic effect of cannabinoids has been shown across a wide variety of animals that are capable of vomiting in response to a toxic challenge.
Several studies have shown that some cannabinoids can relieve nausea, vomiting or both. These are side effects of some cancer treatments, including chemotherapy and radiation therapy.